CYSTEINE: (Kidney Stones)
·
Cysteine-type peptidase activity
Definition: Catalysis of the hydrolysis of peptide
bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a
cysteine residue at the active center acts as a nucleophile.
Synonyms: Synonyms are alternative words or phrases
closely related in meaning to the term name, with an indication of the
relationship between the name and synonym given by the synonym scope.
TYPE IV COLLAGEN: (Alport Syndrome)
Molecular Function:
·
extracellular matrix structural
constituent
Definition: The action of a molecule that contributes
to the structural integrity of the extracellular matrix.
·
extracellular matrix structural
constituent conferring tensile strength
Definition: A constituent of the extracellular matrix
that enables the matrix to resist longitudinal stress.
·
identical protein binding
Definition: Binding to an identical protein or
proteins.
·
metal ion binding
Definition: Binding to a metal ion.
·
platelet-derived growth factor
binding
Definition: Binding to platelet-derived growth factor.
·
protease binding
Definition: Binding to a protease or a peptidase.
Polycystin-1:
Molecular function:
Definition:
Enables the facilitated diffusion of a calcium ion (by an
energy-independent process) involving passage through a transmembrane aqueous
pore or channel without evidence for a carrier-mediated mechanism.
Definition:
Binding to a carbohydrate, which includes monosaccharides,
oligosaccharides and polysaccharides as well as substances derived from
monosaccharides by reduction of the carbonyl group (alditols), by oxidation of
one or more hydroxy groups to afford the corresponding aldehydes, ketones, or
carboxylic acids, or by replacement of one or more hydroxy group(s) by a
hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
·
protein domain
specific binding
Definition:
Binding to a specific domain of a protein.
Definition:
Binding to a protein kinase, any enzyme that catalyzes the
transfer of a phosphate group, usually from ATP, to a protein substrate.
·
transmembrane
transporter binding
Definition:
Binding to a transmembrane transporter, a protein or protein
complex that enables the transfer of a substance, usually a specific substance
or a group of related substances, from one side of a membrane to the other
·
Wnt-activated
receptor activity
Definition:
Combining with a Wnt protein and transmitting the signal
across the plasma membrane to initiate a change in cell activity.
V2
vasopressin:
Molecular function:
·
G
protein-coupled receptor activity
Definition:
Combining with an extracellular signal and transmitting the
signal across the membrane by activating an associated G-protein; promotes the
exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein
complex.
Definition:
Binding to a peptide, an organic compound comprising two or
more amino acids linked by peptide bonds.
·
vasopressin
receptor activity
Definition:
Combining with vasopressin to initiate a change in cell
activity.
Siderocalin:
Molecular function:
Definition:
Binding to enterobactin.
Definition:
Binding to an identical protein or proteins.
Definition:
Binding to an iron (Fe) ion.
Definition:
Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule.
